Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
E1P (2ZBD) and E2P (1WPG) states of SERCA. The A-Domain (red) rotates about 90° in the E2P state. P-Domain (green) has three helical regions P5,P6 and P7 (purple) which interacts with the A3 helix (blue) in the E2P state. N-Domain (yellow) also moves to accommodate A-Domain rotation. Rearrangements also take place in the transmembrane helices (gray)
