Figure 3. MTS proliferation assay in neuroblastoma cell lines exposed to ellipticine and pinafide.
Proliferation of MYCN amplified (panel A) or MYCN non amplified (panel B) cells in the presence of increasing concentrations of Ellipticine and Pinafide, as indicated. Note that cell viability is only reduced by high concentrations (250-500nM) of pinafide, in a MYCN-independent manner. Neuroblastoma cell lines were generally resistant to the killing effect of ellipticine. Error bars indicate standard deviations.