Skip to main content
. 2012 May 25;3(5):568–575. doi: 10.18632/oncotarget.526

Figure 2. Altered HSPG-related gene expression in human GBM.

Figure 2

The mean expression of a number of HSPG-related genes, including HSPG core proteins (GPCs, SDCs, AGRN, SRGN, and HSPG2) and modifying enzymes (HPSE and SULFs) are altered in GBM relative to normal controls. Bars represent the mean ratio of log2(Tumor/Normal) +/− SEM gene expression. Upregulated (red) and down regulated, log2 (Tumor/Normal) greater than or equal to 0.5 or less than or equal to -0.5, respectively. TCGA Data Portal [71]; http://cancergenome.nih.gov. (n=170 human tumors). GPC, glypican; SDC, syndecan; SULF, extracellular sulfatase; AGRN, agrin; SRGN, serglycin; HSPG2, perlecan; HSPE, heparanase.

HHS Vulnerability Disclosure