Table 1.

A comparison among Nadkarni et al. [12] model, Volman et al. [13] model and the proposed model

Signaling processes modeled	Volman et al. [13]	Nadkarni et al. [12]	This paper
Bouton Ca2 +	No	Yes	Yes
Bouton IP3	No	No	Yes
Synaptic vesicle / glutamate	Yes / No	Yes / No	Yes / Yes
Astrocytic Ca2 +	Yes	Yes	Yes
Astrocytic IP3	Yes	Yes	Yes
Extra-synaptic vesicle / glutamate	No	No	Yes / Yes
Post-synaptic current / potential	Yes / No	Yes / No	Yes / Yes