Table 4.

Parameters used for glutamate dynamics in the bouton and cleft

Symbol	Description	Value	Reference
A	Ca2 +  association rate constant	0.3 μM ms − 1	[36]
β	Ca2 +  dissociation rate constant	3 ms − 1	[36]
γ	Isomerization rate constant (forward)	30 ms − 1	[36]
Δ	Isomerization rate constant (backward)	8 ms − 1	[36]
τrec	Vesicle recovery time constant	800 ms	[29]
τinac	Vesicle inactivation time constant	3 ms	[29]
a1	Ca2 +  concentration at which λ is halved	50 μM	See text
a2	Slope factor of spontaneous release rate λ	5 μM	See text
a3	Maximum spontaneous release rate	0.85 ms − 1	See text
nv	Number of docked vesicles	2	[50]
gv	Glutamate concentration in single vesicles	60 mM	[54]
gc	Glutamate clearance rate constant	10 ms − 1	[31]