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. 2011 Nov 8;4(2):201–212. doi: 10.1159/000332142

Fig. 3.

Fig. 3

IL-8 secretion and calcium fluxes of neutrophils stimulated by staphylococcal culture filtrates are largely Agr and FPR2/ALX-dependent. IL-8 release from neutrophils induced by culture filtrates from S. aureus USA300 and the isogenic Agr mutant (a), S. aureus RN6390 and the isogenic Agr mutant RN6911 (b) and S. epidermidis and the isogenic Agr mutant (c) in the presence or absence of FLIPr. d Calcium influx in neutrophils stimulated by S. aureus or S. epidermidis culture filtrates in the presence or absence of FLIPr. Data represent means ± SEM of 3 independent experiments with neutrophils of different persons and at least 3 different culture filtrates. * p < 0.05; ** p < 0.005; *** p < 0.001. n.s. = Not significant.