Table 4.
Hemodynamic parameters and oxygenation. EVLWI: extravascular lung water index; CI: cardiac index; AP mean: mean arterial pressure; CVP: central venous pressure; GEDI: global enddiastolic volume index; SVI: stroke volume index; compliance: pulmonary compliance; NE: norepinephrine administration; ∗difference to BL in analysis of variance (ANOVA) (P < 0.05). BL: directly after induction of anesthesia; OLVimpl15: 15 minutes after beginning OLV; OLVterm15: 15 minutes after cessation of OLV; 6postop: 6 hours after surgery; 12postop: 12 hours after surgery; 24postop: 24 hours after surgery.
| BL | OLVimpl15 | OLVterm15 | 6postop | 12postop | 24postop | |
|---|---|---|---|---|---|---|
| EVLWIT [mL/kg] | 7.8 ± 2.5 | 8.4 ± 3.9 | 8.5 ± 2.5 | 8.2 ± 2.9 | 8.7 ± 2.6 | 8.1 ± 2.4 |
| EVLWIL [mL/kg] | 7.9 ± 1.7 | 8.1 ± 3.2 | 8.5 ± 2.5 | 7.8 ± 2.4 | 8 ± 1.8 | 7.2 ± 1.9 |
| EVLWIE [mL/kg] | 7.8 ± 3 | 8.5 ± 3.4 | 8.6 ± 2.6 | 8.5 ± 3.1 | 8.98 ± 3 | 9.1 ± 2.5 |
|
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| paO2/FiO2-ratioT [mmHg] | 419 ± 122 | 186 ± 94∗ | 334 ± 92∗ | n.d. | n.d. | n.d. |
| paO2/FiO2-ratioL [mmHg] | 462 ± 140 | 202 ± 105∗ | 338 ± 112∗ | n.d. | n.d. | n.d. |
| paO2/FiO2-ratioE [mmHg] | 389 ± 101 | 174 ± 87∗ | 332 ± 80 | 330 ± 111 | 329 ± 105 | 303 ± 74∗ |
|
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| CIT [L/min/m2] | 2.8 ± 0.9 | 3.6 ± 0.9∗ | 3.5 ± 0.8 | 3.5 ± 0.9∗ | 3.6 ± 0.9 | 3.5 ± 0.9 |
| CIL [L/min/m2] | 3 ± 0.9 | 3.4 ± 0.66 | 3.5 ± 0.8 | 3.6 ± 1.1 | 3.9 ± 1.2 | 3.6 ± 1.2 |
| CIE [L/min/m2] | 2.7 ± 0.9 | 3.7 ± 1∗ | 3.5 ± 0.7 | 3.5 ± 0.6 | 3.5 ± 0.7 | 3.4 ± 0.6 |
|
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| AP meanT [mmHg] | 78.7 ± 15 | 74.9 ± 14.1 | 73 ± 12.1 | 78.9 ± 14.1 | 73.9 ± 16.1 | 76.6 ± 8.2 |
| AP meanL [mmHg] | 84.8 ± 13.3 | 84.7 ± 12.6 | 80.1 ± 14.1 | 85.9 ± 11.7 | 81.3 ± 14.2 | 81.4 ± 6.9 |
| AP meanE [mmHg] | 74.5 ± 15 | 68.2 ± 11 | 68.1 ± 7.8 | 74 ± 13.7 | 69.5 ± 15.9 | 73.8 ± 7.7 |
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| CVPT [mmHg] | 7.4 ± 2 | 7.3 ± 2.9 | 6.6 ± 2.7 | 6.1 ± 2 | 5.8 ± 2.4 | 6 ± 2.2 |
| CVPL [mmHg] | 7.9 ± 0.3 | 7.2 ± 2.5 | 6.4 ± 2.3 | 5.9 ± 2.2 | 5.4 ± 1.2 | 5.5 ± 1.5 |
| CVPE [mmHg] | 7 ± 2.6 | 7.4 ± 3.3 | 6.8 ± 3 | 6.3 ± 1.9 | 6 ± 2.9 | 6.2 ± 2.6 |
|
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| GEDIT [mL/m2] | 673 ± 169 | 642 ± 152 | 633 ± 144 | 649 ± 114 | 665 ± 124 | 658 ± 123 |
| GEDIL [mL/m2] | 702 ± 167 | 694 ± 121 | 689 ± 170 | 670 ± 93 | 657 ± 138 | 640 ± 101 |
| GEDIE [mL/m2] | 653 ± 173 | 607 ± 165 | 594 ± 112 | 635 ± 128 | 670 ± 119 | 669 ± 137 |
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| SVIT [mL/m2] | 40.2 ± 11.1 | 48.4 ± 12.4 | 46.9 ± 15.3 | 49.6 ± 13.6 | 49.7 ± 13.8 | 47.3 ± 13.9 |
| SVIE [mL/m2] | 38.9 ± 10.0 | 50.2 ± 13.7 | 46.7 ± 16.1 | 47.8 ± 12.3 | 47.1 ± 12.5 | 46.5 ± 12.8 |
| SVIL [mL/m2] | 42.0 ± 12.7 | 46.1 ± 10.4 | 47.1 ± 14.9 | 52.0 ± 15.5 | 53.1 ± 15.3 | 48.5 ± 15.8 |
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| ComplianceT [L/cmH2O] | 0.049 ± 0.013 | 0.023 ± 0.006∗ | 0.046 ± 0.012 | n.d. | n.d. | n.d. |
| ComplianceL [L/cmH2O] | 0.055 ± 0.014 | 0.024 ± 0.006∗ | 0.045 ± 0.013 | n.d. | n.d. | n.d. |
| ComplianceE [L/cmH2O] | 0.046 ± 0.01 | 0.022 ± 0.005∗ | 0.046 ± 0.012 | 0.039 ± 0.013 | 0.052 ± 0.023 | 0.062 ± 0.024 |
|
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| NET [μg/kg/min] | 0.07 ± 0.02 | 0.12 ± 0.02 | 0.08 ± 0.01 | 0.04 ± 0.02 | 0.03 ± 0.01 | 0.02∗ ± 0.01 |
| NEL [μg/kg/min] | 0.05 ± 0.01 | 0.09 ± 0.02 | 0.06 ± 0.02 | 0.01 ± 0.01 | 0.01 ± 0.01 | 0.008∗ ± 0.01 |
| NEE [μg/kg/min] | 0.08 ± 0.01 | 0.14 ± 0.01 | 0.09 ± 0.01 | 0.06 ± 0.02 | 0.04 ± 0.01 | 0.03∗ ± 0.01 |