Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Possible mechanisms of HSC transdifferentiation. HSCs might directly transdifferentiate into another cell type (lower arrow) or through transient reprogramming in certain conditions. Loss of p53 might promote transient reprogramming for HSC transdifferentiation.
