Table 1.
B.W. | Liver weight | Liver weight/ B.W. (%) | Plasma TG | Liver TG | ||
---|---|---|---|---|---|---|
mPParα | Control | 23.9 ± 0.91 | 0.88 ± 0.11 | 3.68 ± 0.38 | 79.4 ± 16.3 | 14.8 ± 1.53 |
DBP 2.5 | 25.9 ± 2.05 | 1.08 ± 0.13 | 4.14 ± 0.17 | 89.9 ± 24.8 | 12.5 ± 2.76 | |
DBP 5.0 | 26.7 ± 2.01 | 1.20 ± 0.10* | 4.49 ± 0.40 | 113.9 ± 40.4 | 11.4 ± 1.68 | |
DEHP 2.5 | 22.1 ± 1.82 | 1.13 ± 0.11* | 5.09 ± 0.24* | 82.6 ± 13.8 | 11.6 ± 1.56 | |
DEHP 5.0 | 22.9 ± 0.92 | 1.26 ± 0.06* | 5.54 ± 0.33* | 84.0 ± 24.5 | 6.8 ± 0.90* | |
DEHA 2.5 | 25.9 ± 0.85 | 1.20 ± 0.07* | 4.63 ± 0.22* | 136.9 ± 15.9 | 11.4 ± 0.90 | |
DEHA 5.0 | 24.2 ± 1.81 | 1.28 ± 0.18* | 5.27 ± 0.35* | 119.5 ± 36.3 | 7.5 ± 1.76* | |
| ||||||
hPParα | Control | 22.7 ± 2.20 | 1.04 ± 0.06 | 4.59 ± 0.25 | 97.0 ± 23.6 | 24.4 ± 5.51# |
DBP 2.5 | 25.0 ± 2.32 | 1.07 ± 0.08 | 4.29 ± 0.18 | 127.0 ± 35.0 | 22.6 ± 4.66 | |
DBP 5.0 | 23.1 ± 4.51 | 1.05 ± 0.28 | 4.76 ± 0.29 | 95.1 ± 26.0 | 31.9 ± 19.31 | |
DEHP 2.5 | 23.8 ± 2.58 | 1.12 ± 0.17 | 4.69 ± 0.25 | 111.5 ± 28.0 | 20.6 ± 4.66 | |
DEHP 5.0 | 21.6 ± 2.58 | 1.03 ± 0.17 | 4.52 ± 0.37 | 67.8 ± 35.0 | 30.9 ± 4.24* | |
DEHA 2.5 | 24.9 ± 1.03 | 1.12 ± 0.08 | 4.48 ± 0.14 | 142.3 ± 59.9 | 23.1 ± 1.98 | |
DEHA 5.0 | 24.7 ± 2.94 | 1.23 ± 0.17 | 4.98 ± 0.25 | 176.0 ± 41.0* | 28.4 ± 2.73 |
B.W: body weight.
Each value represents mean ± S.D. *Significantly different from respective controls (P < 0.05). #Significantly different from mPPARα controls (P < 0.05).