Figure 3.

a. Na_V1.7 levels in DRG of diabetic animals inoculated with QHmiNa_V demonstrates reduction in protein compared to QHmiSc 4 weeks after inoculation (*** p < 0.005). Data presented as ratio to β-actin (βa). b. In situ hybridization using a probe specific for Na_V1.7 in DRG from diabetic animals, without treatment or inoculated with QHmiSc or QHmiNa_V as indicated. A sense probe showed no staining. The average optical density of DRG neurons in each condition was determined using a PC based image analysis program (MCID). * p < 0.05; ** p < 0.01.