Table 4.
Mild Insufficiency of Kidney Function Risk Associated with Malondialdehyde Levels Stratified by Gender, Age, Body Mass Index, Alcohol Intake, Tobacco Consumption, Sleep Quality, and Physical Activity
| |
|
|
ORa (95%CI) |
||||
|---|---|---|---|---|---|---|---|
| MIKF | Nb | <2.90 | 2.90–3.43 | 3.43–4.01 | ≥4.01 | p value | |
| Gender | male | 400/612 | 1.00 | 1.32 (0.86–2.03) | 1.41 (0.91–2.18) | 1.85 (1.21–2.82) | 0.004 |
| female | 160/405 | 1.00 | 1.15 (0.61–2.15) | 1.33 (0.71–2.49) | 1.92 (1.01–3.63) | 0.046 | |
| Age(years) | <25 | 6/62 | 1.00 | N/A | N/A | N/A | N/A |
| 25–65 | 443/943 | 1.00 | 1.30 (0.90–1.86) | 1.36 (0.94–1.98) | 1.92 (1.34–2.75) | 0.000 | |
| ≥65 | 111/12 | 1.00 | 3.53 (0.18–71.21) | 1.94 (0.17–22.15) | 4.80 (0.26–87.67) | 0.289 | |
| BMI (kg/m2) | <25 | 343/693 | 1.00 | 1.24 (0.81–1.90) | 1.40 (0.91–2.16) | 1.96 (1.27–3.04) | 0.002 |
| ≥25 | 217/324 | 1.00 | 1.58 (0.85–2.91) | 1.58 (0.85–2.96) | 2.03 (1.13–3.65) | 0.017 | |
| Alcohol intake | no | 168/314 | 1.00 | 0.95 (0.49–1.87) | 1.38 (0.72–2.65) | 2.05 (1.08–3.90) | 0.028 |
| yes | 302/491 | 1.00 | 1.61 (1.00–2.59) | 1.47 (0.91–2.39) | 1.99 (1.24–3.20) | 0.005 | |
| Tobacco consumption | no | 226/390 | 1.00 | 1.06 (0.61–1.86) | 1.04 (0.58–1.84) | 1.51 (0.88–2.58) | 0.131 |
| yes | 255/432 | 1.00 | 1.69 (1.00–2.87) | 1.81 (1.07–3.08) | 2.10 (1.23–3.58) | 0.007 | |
| Sleep quality | well | 402/606 | 1.00 | 1.52 (0.99–2.33) | 1.44 (0.93–2.22) | 2.18 (1.43–3.30) | 0.000 |
| not too well | 106/221 | 1.00 | 1.47 (0.66–3.27) | 1.69 (0.72–4.00) | 1.52 (0.65–3.55) | 0.329 | |
| Physical activity | sedentary | 259/610 | 1.00 | 1.22 (0.74–2.02) | 1.81 (1.10–2.99) | 2.10 (1.29–3.41) | 0.003 |
| active | 240/205 | 1.00 | 1.42 (0.77–2.60) | 0.90 (0.48–1.68) | 1.84 (1.00–3.40) | 0.051 | |
a
Adjusted for age, gender, alcohol intake, tobacco consumption, sleep quality, physical activity, BMI, systolic blood pressure, diastolic blood pressure, blood glucose level, and serum levels of cholesterol, triglyceride, ALT and AST.
Nb=MIKF/normal kidney function.
MIKF, Mild insufficiency of kidney function; BMI, body mass index; OR, odds ratio; CI, confidence interval; N/A, not available (cases not enough for multinomial logistic regression).