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PET study in U87MG tumor-bearing mice. Decay-corrected whole-body coronal microPET images of athymic nude mice bearing U87MG tumors at 2 h p.i. of [18F]FBEM-scVEGF (3.7MBq), unblocked (A) and blocked (B). (C) Tumor-to-kidney and tumor-to-muscle ratios at 2 h p.i. of [18F]FBEM-scVEGF. (D) Uptake values at 2 h p.i. in the U87MG tumor in the presence or absence of scVEGF protein.
