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PET study in 4T1 tumor-bearing mice. Decay-corrected whole-body coronal microPET images of Balb/C mice bearing 4T1 tumors at 2 h p.i. of [18F]-FBEM-scVEGF (3.7MBq), unblocked (A) and blocked (B). (C) Uptake values at 2 h p.i. in the 4T1 tumor in the presence or absence of scVEGF protein. (D) Biodistribution of [18F]FBEM-scVEGF in Balb/C mice bearing subcutaneous 4T1 tumors after microPET imaging at 2 h time point (n = 6).
