. Author manuscript; available in PMC: 2012 Jul 3.

Published in final edited form as: Cancer Metastasis Rev. 2010 Sep;29(3):503–510. doi: 10.1007/s10555-010-9240-5

Table 1.

Selected molecular targets for nutraceuticals in late-stage cancer

Molecular target	Agent identified with inhibition	Reference
COX-2	EGCG, curcumin, resveratrol	[40, 57, 58, 81]
DNMTs	EGCG	[59]
EGFR	Curcumin, resveratrol	[62]
HDACs	EGCG	[60]
ERs	Genistein	[69]
MMPs	Eugenol	[23]
NFκβ	Curcumin, diosgenin, EGCG, eugenol	[20, 23, 56, 58]
TIMP-2	Eugenol	[23]
VEGF	EGCG, curcumin, eugenol	[23, 51, 81]