Table 5.
The base case economic evaluation results
| Base case ICER calculations | Threshold analysis*: probability of cost-effective at alternative values of willingness to pay for a QALY (%) |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Mean total cost (£) | Incremental cost (£) | Mean QALY | Incremental QALY | ICER (£/QALY) |
£10, 000 |
£20, 000 |
£30, 000 |
£50, 000 |
|
| Fluid loading | 10,373 | 0.3527 | 84.4 | 86.5 | 89.4 | 92.0 | |||
| Fluid control | 11,739 | -1,366 | 0.3175 | 0.0352 | Dominated | 15.6 | 13.5 | 10.6 | 8.0 |
| Adjusted differences (95% CI; P-value)* |
-2,047 (-6,947 to 2,854; P = 0.413) |
0.0431 (-0.0171 to 0.1033; P = 0.161) |
|||||||
CI, confidence interval; ICER, incremental cost-effectiveness ratio; QALY, quality adjusted life year.
* Adjusted for minimisation variables and baseline EQ-5D score and based on 1,000 bootstrap iterations.