Table 1.

The measured volume change of the target volumes of interest observed in the weekly CT images for the lung case. The structures were contoured on the planning CT and deformed to the weekly CT images using in-house deformable image registration software. For the selected patient case, a reduction of 41% of the gross tumor volume (GTV-T50 and IGTV) and 21% of the clinical target volume (CTV-T50 and ICTV) was observed.

	Volume [cc] (% Volume Change)
Site (Week)	GTV-T50	CTV-T50	IGTV	ICTV
Lung (week0)	128 (0%)	323 (0%)	148 (0%)	331 (0%)
Lung (week1)	110 (−14%)	300 (−7%)	126 (−15%)	307 (−7%)
Lung (week2)	96 (−25%)	277 (−14%)	110 (−25%)	286 (−14%)
Lung (week3)	90 (−30%)	275 (−15%)	104 (−29%)	282 (−15%)
Lung (week4)	82 (−36%)	264 (−18%)	96 (−35%)	272 (−18%)
Lung (week5)	77 (−40%)	257 (−20%)	90 (−39%)	264 (−20%)
Lung (week6)	76 (−41%)	254 (−21%)	88 (−40%)	262 (−21%)