Table 1. Brain disorders associated with an increased prevalence of insulin resistance/diabetes and/or obesity.

Psychiatric disorders	Schizophrenia Bipolar disorder Major Depressive Disorder
Neurodegenerative Diseases	Alzheimer's disease Vascular Dementia Parkinson's disease Huntington's disease
Congenital neurodegenerative disorders	Prader-Willi Alstrom syndrome Bardet-Biedl syndrome Down's syndrome1 Ataxia-telangiectasia (Louis-Bar syndrome) Niemann-Pick disease Werner syndrome Wolfram syndrome Woodhouse-Sakati syndrome
Other congenital Disorders	Glut1 deficiency Familiar hyperinsulinism Kearns-Sayre syndrome Klinefelter syndrome Feigenbaum syndrome Friedreich ataxia MELAS syndrome Myotonic dystrophy 1 Narcolepsy Thiamine responsive megaloblastic anemia syndrome Spinocerebellar ataxia 3 (Machado-Joseph disease) Spinocerebellar ataxia 6 Turner syndrome