Table 1.

Maximum LOD scores suggestive of linkage (LOD ≥ 1.8) for multipoint quantitative trait linkage analyses of HDL-C, apolipoprotein A-1 and triglyceride levels in American Indian Participants of the Strong Heart Family Study

Phenotype	Center and Model a	Chromosome	Centimorgan	Chromosomal Region	Maximum LOD Score
HDL-C
	Oklahoma, model 2	3	193	3q26.31 – q27.3	1.9
	Arizona, model 1, model 2	6	35–36	6p22.3–p24.3	4.4, 2.8
	Dakotas, model 1	9	110	9q31.1–q31.3	1.9
	Oklahoma, model 2	9	101	9q22.32–q31.1	2.0
apolipoprotein A-1
	Dakotas, model 1	2	214	2q33.3–q35	2.2
	Arizona, model 1, model 2	6	36	6p22.3–p24.3	3.2, 2.1
	Oklahoma, model 2	7	92	7q21.11–q21.13	1.9
	Dakotas, model 1	9	99	9q22.2	3.0
	Dakotas, model 2	9	103	9q22.2–q31.1	2.5
	Dakotas, model 2	12	162	12q24.32	2.1
Triglycerides
	Arizona, model 1, model 2	4	168–169	4q32.3–q34.1	1.9, 3.0
	Arizona, model 1	6	87	6p12.1–q14.1	2.9
	Arizona, model 2	6	75	6p12.1–p21.2	2.6
	Arizona, model 1, model 2	10	163–164	10q26.2–q26.3	2.9, 3.7
	Oklahoma, model 1	11	67	11q12.1–q13.2	1.8
	Arizona, model 1	15	44	15q15.1–q21.1	2.0
	Dakotas, model 1, model 2	15	65–68	15q22.1–q22.31	3.8, 2.2
	Dakotas, model 1	18	40	18p11.21–q12.1	1.9
	Oklahoma, model 2	21	10	21q21.1	2.0

^aModel 1: adjustment for sex, age, and stratified by field center.

Model 2: additional adjustments for waist circumference, current smoking status, current consumption of alcohol, current estrogen use, lipid treatment status, impaired fasting glucose and diabetes status.