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. Author manuscript; available in PMC: 2012 Jul 3.
Published in final edited form as: Exp Eye Res. 2008 Dec 6;88(5):859–879. doi: 10.1016/j.exer.2008.11.018

Figure 9.

Figure 9

Comparison of active vs. inactive 266 and 1411 hhRzs to promote opsin knockdown. A single catalytic core mutation (G5C) was used to inactivate the catalytic function of the hhRz to test for reversal of significant KD effects in active 266 and 1411 pGVAL-hhRzs (Number of experiments for each condition: Active hhRz 266: 23; Inactive hhRz 266: 7; Active hhRz 1411: 19; Inactive hhRz 1411: 3). Pairwise comparisons show no significant differences in KD between the active and inactive hhRzs at site 266 (t = −0.1865, p = 0.8534) and site 1411 (t = −1.588, p = 0.1279).