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. 2012 Jul 3;7(7):e39890. doi: 10.1371/journal.pone.0039890

Figure 1. LPS pretreatment suppressed CNV formation.

Figure 1

Peritoneal injection of low-dose LPS (20 µg) was performed at 4, 3, 2 or 1 days (respectively, Day -4, -3, -2 and -1) before laser irradiation (Day 0), or at 2 days after laser irradiation (Day +2), and the CNV size was evaluated at 10 days after laser treatment (Day 10) (A). In all groups of LPS-pretreated mice, the size of CNV was significantly smaller than that in control mice (B, C). The smallest CNV was shown in the mice given LPS pretreatment 2 days before laser treatment. The bars show means ± SEM. n = 6 mice/group, *P = 0.002 compared with control.