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. 2012 Jul 3;7(7):e39890. doi: 10.1371/journal.pone.0039890

Figure 2. LPS treatment increased serum IL-10 concentration and IL-10 expression in peritoneal macrophages and in the eye.

Figure 2

After peritoneal injection of low-dose LPS, IL-10 expression in the peritoneal macrophages (A) and in the posterior part of the eye (the retina, RPE and choroid) (B) increased, approximately 8-fold and 4-fold, respectively, two days after LPS injection. The bars show means ± SEM. n = 6 mice/group, *P<0.001 compared with control. Serum IL-10 concentration increased (C). n = 6, *P<0.001 compared with baseline. It reached a peak on day 1 and gradually decreased. A significant increase was shown for at least 4 days.