Table 2. Gene Expression Score Component Variability.
Gene/Component | Mean Cp | SD | % Variability | AlgorithmWeight |
TSPAN161 | 33.23783329 | 0.314473 | <1% | 0 |
TMC8 | 27.0491705 | 0.062304 | 1.39% | 0.069 |
CD3D | 28.49725376 | 0.066184 | 1.47% | 0.069 |
SPIB | 31.67462259 | 0.106285 | 1.56% | 0.04521 |
RPL28 | 23.23034338 | 0.046649 | 2.33% | 0.154 |
HNRNPF | 28.04762546 | 0.058873 | 2.35% | 0.123 |
S100A8 | 22.36803951 | 0.052756 | 2.41% | 0.14124 |
CD79B | 29.10833979 | 0.083717 | 2.49% | 0.09179 |
AQP9 | 25.77568108 | 0.06066 | 2.69% | 0.137 |
NCF4 | 26.35784643 | 0.063076 | 2.80% | 0.137 |
S100A12 | 25.22470751 | 0.061538 | 2.82% | 0.14124 |
CLEC4E | 27.10114833 | 0.061894 | 2.83% | 0.14124 |
TLR4 | 27.6331357 | 0.051561 | 3.16% | 0.189 |
CXCR2 | 24.56723698 | 0.057652 | 3.53% | 0.189 |
TFCP2 | 30.40651938 | 0.101976 | 4.06% | 0.123 |
TNFRSF10C | 24.88700233 | 0.07295 | 4.47% | 0.189 |
IL18RAP | 27.81802168 | 0.057736 | 4.67% | 0.24948 |
SLAMF7 | 29.44608773 | 0.074932 | 4.93% | 0.203 |
KCNE3 | 28.91777707 | 0.085435 | 5.23% | 0.189 |
KLRC4 | 29.5726501 | 0.082712 | 5.44% | 0.203 |
TNFAIP6 | 30.22744093 | 0.07769 | 6.28% | 0.24948 |
CASP5 | 31.80418539 | 0.123132 | 9.95% | 0.24948 |
AF289562 | 33.62904299 | 0.290804 | 23.17% | 0.246 |
Despite high having a high SD, TSPAN16 contributes little to variability in the GES due to its low weight in the control sample used; in clinical samples TSPAN16 is weighted according to sex [8].