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. 2012 Jul 3;7(7):e39871. doi: 10.1371/journal.pone.0039871

Table 1. Genes up-regulated by STATC.

Symbol Definition Fold change STAT3C v AdGFP
LBP Lipopolysaccharide binding protein 10.31
IL1RL1 Interleukin 1 receptor-like 1 9.95
SAA2 Serum amyloid A2 8.37
CCL8 Chemokine (C-C motif) ligand 8 7.98
NFE2 Nuclear factor (erythroid-derived 2) 6.67
SERPINB4 Serpin peptidase inhibitor clade B (ovalbumin), member 4 5.99
PMAIP1 Phorbol-12-myristate-13-acetate-induced protein 1 5.67
F3 Coagulation factor III (thromboplastin, tissue factor) 5.18
EFNA1 Ephrin A1 4.96
IL6 Interleukin 6 (interferon, beta 2) 4.92
CHI3L2 Chitinase 3-like 2 4.55
SOCS3 Suppressor of cytokine signaling 3 4.55
SAA1 Serum amyloid A1 4.43
FLJ22447 PREDICTED: hypothetical gene supported by AK026100 4.42
WWC1 WW and C2 domain containing 1 4.33
SERPINB3 Serpin peptidase inhibitor clade B (ovalbumin), member 3 4.27
NAMPT Nicotinamide phosphoribosyltransferase 4.25
MT1M Metallothionein 1 M 4.22
CH25H Cholesterol 25-hydroxylase 4.08
PIM1 pim-1 oncogene 4.07
STEAP4 STEAP family member 4 3.76
KIAA1199 KIAA1199 3.68
CA2 Carbonic anhydrase II 3.65
TNC Tenascin C 3.58
ANGPTL4 Angiopoietin-like 4 3.39
RCAN1 Regulator of calcineurin 1 3.39
ACHE Acetylcholinesterase 3.38
HP Haptoglobin 3.33
GSDMC Gasdermin C 3.27
IL1R2 Interleukin 1 receptor, type II 3.22
BCL3 B-cell CLL/lymphoma 3 3.18
IL1R1 Interleukin 1 receptor, type I 3.03
RGS16 Regulator of G-protein signaling 16 3
MAFB v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) 2.99
TDO2 Tryptophan 2,3-dioxygenase (TDO2) 2.93
KRTAP1–5 Keratin associated protein 1–5 2.92
SLC2A3 Solute carrier family 2 (facilitated glucose transporter), member 3 2.92
PLAU Plasminogen activator, urokinase 2.90
C10orf10 Chromosome 10 open reading frame 10 2.90
IGF1 Insulin-like growth factor 1 (somatomedin C) 2.87
GLDN Gliomedin 2.83
G0S2 G0/G1switch 2 2.83
TNFRSF21 Tumor necrosis factor receptor superfamily, member 21 2.82
SERPINA3 Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 2.78
CXCL5 Chemokine (C-X-C motif) ligand 5 2.76
MT1X Metallothionein 1X 2.74
STEAP1 PREDICTED: Six transmembrane epithelial antigen of the prostate 1 2.74
CCL7 Chemokine (C-C motif) ligand 7 (CCL7) 2.69
INSIG1 Insulin induced gene 1 2.68
NOD1 Nucleotide-binding oligomerization domain containing 1 2.64

The table lists the 50 most highly significantly up-regulated transcripts in MSC STAT3C compared to MSC AdGFP (with p<0.01 cutoff using one way ANOVA with Benjamini-Hochberg multiple testing correction). Values shown are the medians from the five donors.