Table 1. Genes up-regulated by STATC.
Symbol | Definition | Fold change STAT3C v AdGFP |
LBP | Lipopolysaccharide binding protein | 10.31 |
IL1RL1 | Interleukin 1 receptor-like 1 | 9.95 |
SAA2 | Serum amyloid A2 | 8.37 |
CCL8 | Chemokine (C-C motif) ligand 8 | 7.98 |
NFE2 | Nuclear factor (erythroid-derived 2) | 6.67 |
SERPINB4 | Serpin peptidase inhibitor clade B (ovalbumin), member 4 | 5.99 |
PMAIP1 | Phorbol-12-myristate-13-acetate-induced protein 1 | 5.67 |
F3 | Coagulation factor III (thromboplastin, tissue factor) | 5.18 |
EFNA1 | Ephrin A1 | 4.96 |
IL6 | Interleukin 6 (interferon, beta 2) | 4.92 |
CHI3L2 | Chitinase 3-like 2 | 4.55 |
SOCS3 | Suppressor of cytokine signaling 3 | 4.55 |
SAA1 | Serum amyloid A1 | 4.43 |
FLJ22447 | PREDICTED: hypothetical gene supported by AK026100 | 4.42 |
WWC1 | WW and C2 domain containing 1 | 4.33 |
SERPINB3 | Serpin peptidase inhibitor clade B (ovalbumin), member 3 | 4.27 |
NAMPT | Nicotinamide phosphoribosyltransferase | 4.25 |
MT1M | Metallothionein 1 M | 4.22 |
CH25H | Cholesterol 25-hydroxylase | 4.08 |
PIM1 | pim-1 oncogene | 4.07 |
STEAP4 | STEAP family member 4 | 3.76 |
KIAA1199 | KIAA1199 | 3.68 |
CA2 | Carbonic anhydrase II | 3.65 |
TNC | Tenascin C | 3.58 |
ANGPTL4 | Angiopoietin-like 4 | 3.39 |
RCAN1 | Regulator of calcineurin 1 | 3.39 |
ACHE | Acetylcholinesterase | 3.38 |
HP | Haptoglobin | 3.33 |
GSDMC | Gasdermin C | 3.27 |
IL1R2 | Interleukin 1 receptor, type II | 3.22 |
BCL3 | B-cell CLL/lymphoma 3 | 3.18 |
IL1R1 | Interleukin 1 receptor, type I | 3.03 |
RGS16 | Regulator of G-protein signaling 16 | 3 |
MAFB | v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) | 2.99 |
TDO2 | Tryptophan 2,3-dioxygenase (TDO2) | 2.93 |
KRTAP1–5 | Keratin associated protein 1–5 | 2.92 |
SLC2A3 | Solute carrier family 2 (facilitated glucose transporter), member 3 | 2.92 |
PLAU | Plasminogen activator, urokinase | 2.90 |
C10orf10 | Chromosome 10 open reading frame 10 | 2.90 |
IGF1 | Insulin-like growth factor 1 (somatomedin C) | 2.87 |
GLDN | Gliomedin | 2.83 |
G0S2 | G0/G1switch 2 | 2.83 |
TNFRSF21 | Tumor necrosis factor receptor superfamily, member 21 | 2.82 |
SERPINA3 | Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 2.78 |
CXCL5 | Chemokine (C-X-C motif) ligand 5 | 2.76 |
MT1X | Metallothionein 1X | 2.74 |
STEAP1 | PREDICTED: Six transmembrane epithelial antigen of the prostate 1 | 2.74 |
CCL7 | Chemokine (C-C motif) ligand 7 (CCL7) | 2.69 |
INSIG1 | Insulin induced gene 1 | 2.68 |
NOD1 | Nucleotide-binding oligomerization domain containing 1 | 2.64 |
The table lists the 50 most highly significantly up-regulated transcripts in MSC STAT3C compared to MSC AdGFP (with p<0.01 cutoff using one way ANOVA with Benjamini-Hochberg multiple testing correction). Values shown are the medians from the five donors.