Table 4. Selected genes associated with OB differentiation and/or function.
Symbol | Definition | Fold change STAT3Cv AdGFP | References |
SAA2 | Serum amyloid A2 | 8.37 | [69] |
EFNA1 | Ephrin A1 | 4.97 | [72], [87] |
IL6 | Interleukin 6 | 4.92 | [88] |
SAA1 | Serum amyloid A1 | 4.43 | [69] |
MT1M | Metallothionein 1 M | 4.22 | [89] |
TNC | Tenascin C | 3.58 | [90] |
RCAN1 | Regulator of calcineurin 1 | 3.39 | [91] |
IL1R2 | Interleukin 1 receptor, type II | 3.23 | [92] |
IL1R1 | Interleukin 1 receptor, type I | 3.04 | [92] |
RGS16 | Regulator of G-protein signalling 16 | 3.00 | [88] |
PLAU | Plasminogen activator, urokinase | 2.90 | [93] |
IGF1 | Insulin-like growth factor 1 | 2.87 | [68], [94] |
CXCL5 | Chemokine (C-X-C motif) ligand 5 | 2.76 | [95] |
MT1X | Metallothionein 1X | 2.73 | [89] |
CCL7 | Chemokine (C-C motif) ligand 7 | 2.67 | [88] |
ALPL | Alkaline phosphatase, liver/bone/kidney | 2.60 | [96] |
RGS2 | Regulator of G-protein signalling 2 | 2.57 | [88] |
DKK1 | Dickkopf homolog 1 (Xenopus laevis) | −2.28 | [97] |
IGFBP1 | Insulin-like growth factor binding protein 1 | 2.27 | [98] |
MT1H | Metallothionein 1 H | 2.24 | [89] |
RGS4 | Regulator of G-protein signalling 4 | −2.17 | [88] |
OSMR | Oncostatin M receptor | 2.05 | [54] |
CCL2 | Chemokine (C-C motif) ligand 2 | 2.03 | [95] |
RUNX2 | Runt-related transcription factor 2 | 1.95 | [99] |
MTE | Metallothionein E | 1.76 | [89] |
PDGFRA | Platelet-derived growth factor receptor-alpha | 1.76 | [100] |
MT1E | Metallothionein 1 E | 1.67 | [89] |
MT1G | Metallothionein 1 G | 1.67 | [89] |
LIFR | Leukemia inhibitory factor receptor alpha | 1.66 | [54] |
IL24 | Interleukin 24 | 1.50 | [88] |
Differentially regulated transcripts in MSC STAT3C compared to MSC AdGFP associated with osteogenic differentiation and function.