Table 2. Comparative analysis of the diagnostic performance of four different antigens in ELISA.
CE Confirmed cases, n = 54 (Sensitivity) | Healthy donors, n = 49 (Specificity) | |||
Overall (n = 54) | B2t negative (n = 12) | B2t positive (n = 42) | ||
HF | 44 (81.5%*) | 4 (33%) | 40 (95.2%) | 46 (93.9%) |
B2t | 42 (77.8%*) | 0 (0%) | 42 (100%) | 47 (95.9%) |
2B2t | 50 (92.6%) | 9 (75%) | 41 (97.6%) | 47 (95.9%) |
4B2t | 43 (79.6%*) | 3 (25%) | 40 (95.2%) | 39 (79.6%*) |
The antigens tested were: hydatid fluid (HF), B2t, 2B2t and 4B2t recombinant proteins. IgG specific antibodies were investigated in patients with cystic echinococccosis (CE) and healthy donors. n = number of samples.
*: indicates significant differences between the HF, B2t or 4B2t and 2B2t-ELISA.