Table 5. Influence of defined clinical variables on the results of four different diagnostic tools (logistic regression).
HF-ELISA | B2t-ELISA | 2B2t-ELISA | IHA | ||||||
B-OR (IC) | M-OR (IC) | B-OR (IC) | M-OR (IC) | B-OR (IC) | M-OR (IC) | B-OR (IC) | M-OR (IC) | ||
NUMBER OF CYSTS | Single | 1 | -- | 1 | 1 | 1 | 1 | 1 | 1 |
Multiple | 2.4 (1.0–5.6) | -- | 2.9 (1.3–6.6) | 2.7 (1.2–6.2) | 2.92 (1.03–8.24) | 2.7 (0.9–7.7) | 3.1 (1.7–5.9) | 3.0 (1.5–5.9) | |
CYST LOCALISATION | Liver | 1 | -- | 1 | -- | 1 | -- | 1 | 1 |
Lung | 2.2 (1.0–5.0) | -- | 1.1 (0.5–2.5) | -- | 0.66 (0.26–1.70) | -- | 3.4 (1.5–7.3) | 2.7 (1.1–6.8) | |
WHO CLASSIFICATION* | CE1 | 1 | 1 | 1 | -- | 1 | -- | 1 | -- |
CE2 to CE4 | 4.0 (1.0–15.5) | 6.6 (1.1–38.5) | 2.2 (0.6–8.0) | -- | 1.05 (0.23–4.83) | -- | 2.2 (0.6–8.2) | -- | |
COMPLICATIONS | No | 1 | 1 | 1 | -- | 1 | -- | 1 | 1 |
Yes | 3.3 (1.4–7.7) | 2.4 (1.0–5.8) | 1.6 (0.8–3.3) | -- | 1.55 (0.64–3.73) | -- | 3.4 (1.8–6.5) | 2.9 (1.5–5.9) | |
FIRST CE | Yes | 1 | -- | 1 | -- | 1 | -- | 1 | -- |
No | 3.7 (0.0) | -- | 1.6 (0.4–5.6) | -- | 2.90 (0.37–22.78) | -- | 2.0 (0.8–5.1) | -- | |
SERUM COLLECTION | Before tr. | 1 | 1 | 1 | 1 | 1 | -- | 1 | 1 |
After tr. | 8.0 (1.8–34.7) | 6.6 (1.5–29.1) | 2.9 (1.1–7.4) | 2.6 (1.0–6.7) | 1.69 (0.59–4.79) | -- | 3.0 (1.6–5.7) | 2.6 (1.3–5.1) |
The association and influence of the clinical variables enumerated in the first column on the sensitivity of the hydatid fluid (HF)-, B2t- and 2B2t-ELISAs and of a commercial IHA kit was statistically assessed. B-OR: odds ratio in the bivariate, and M-OR in the multivariant regression analysis. IC: 95% confidence interval. Statistically significant differences (P≤0.050) are shown in the table (in bold). tr.: treatment.