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. 2012 Mar 6;32(4):663–669. doi: 10.1007/s10875-012-9656-5

Table VIII.

Pharmacokinetic parameters of specific antibodies in patients infused every 4 weeks

Tetanus (N = 16) (IU/mL) H. influenzae b (N = 15) (mg/L) S. pneumoniae serotypes (μg/mL) (N = 16)
14 19A 23F
Elimination half-life (days) 83.76 (n = 14) 25.16a (n = 14) 40.77 (n = 15) 60.04 (n = 15) 29.98 (n = 14)
Cmax (units) 6.96 6.62 14.62 46.14 36.38
Tmax (days) 0.131 0.644 1.821 1.861 1.682
AUC 0-t (units*days) 142.48 (n = 14) 96.09 (n = 14) 253.99 (n = 15) 1026.63 (n = 15) 563.89 (n = 15)

aOutlying value of patient 6003 was excluded from calculation.