Table 2.

Accumulation of globin mRNA following treatment with MTH of T9W infected ErPCs from thalassemic patients

Genotype	Treatment	Globin mRNA increase
		α-Globin mRNA	γ-Globin mRNA	β-Globin mRNA
β039/β039	MTH	1.02 ± 0.31	2.36 ± 0.55	0.95 ± 0.22
	T9W	1.15 ± 0.41	1.08 ± 0.35	2.32 ± 0.41
	T9W + MTH	1.03 ± 0.21	1.85 ± 0.28	2.12 ± 0.44

Data represent the fold changes (average ± S.D.) of the indicated mRNAs in respect to control untreated ErPCs. T9W was used at MOI generating an average of one integration/genome. MTH was used at 50 nM. Number of β⁰39/β⁰39 samples = 5