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. 2012 Mar 31;91(8):1201–1213. doi: 10.1007/s00277-012-1430-5

Table 3.

Effects of treatment of ErPCs from homozygous β039-thalassemic patients on hemoglobin production

Genotype Hemoglobin (−) T9W MTH T9W + MTH
β039/β039 HbF 51.99 44.06 61.91 58.40
α-peak 16.91 7.61 7.37 2.32
HbA 3.29 24.01 2.9 21.45
HbA2 27.64 24.27 27.80 17.79
β039/β039 HbF 32.43 29.93 51.05 43.31
α-peak 35.37 30.65 24.19 19.15
HbA 0.46 10.93 0.32 14.98
HbA2 31.12 27.91 24.09 22.14
β039/β039 HbF 34.68 28.21 45.34 31.06
α-peak 28.03 18.33 23.01 15.72
HbA 0.63 23.05 0.44 25.15
HbA2 36.35 29.85 30.33 27.56
β039/β039 HbF 25.19 19.91 60.01 53.13
α-peak 11.31 5.78 6.12 2.37
HbA 3.64 24.42 2.65 17.42
HbA2 59.70 49.33 30.45 26.96
β039/β039 HbF 48.41 31.74 67.77 40.44
α-peak 25.91 8.26 14.82 5.91
HbA 1.05 44.71 1.84 41.47
HbA2 23.99 14.93 15.39 11.79

Data represent the percent of the indicated hemoglobins (HbF, HbA, and HbA2). The α peak has been identified as a HPLC peak containing α-globin. T9W was used at MOI generating an average of one integration/genome. MTH was used at 50 nM