Table 3.
Genotype | Hemoglobin | (−) | T9W | MTH | T9W + MTH |
---|---|---|---|---|---|
β039/β039 | HbF | 51.99 | 44.06 | 61.91 | 58.40 |
α-peak | 16.91 | 7.61 | 7.37 | 2.32 | |
HbA | 3.29 | 24.01 | 2.9 | 21.45 | |
HbA2 | 27.64 | 24.27 | 27.80 | 17.79 | |
β039/β039 | HbF | 32.43 | 29.93 | 51.05 | 43.31 |
α-peak | 35.37 | 30.65 | 24.19 | 19.15 | |
HbA | 0.46 | 10.93 | 0.32 | 14.98 | |
HbA2 | 31.12 | 27.91 | 24.09 | 22.14 | |
β039/β039 | HbF | 34.68 | 28.21 | 45.34 | 31.06 |
α-peak | 28.03 | 18.33 | 23.01 | 15.72 | |
HbA | 0.63 | 23.05 | 0.44 | 25.15 | |
HbA2 | 36.35 | 29.85 | 30.33 | 27.56 | |
β039/β039 | HbF | 25.19 | 19.91 | 60.01 | 53.13 |
α-peak | 11.31 | 5.78 | 6.12 | 2.37 | |
HbA | 3.64 | 24.42 | 2.65 | 17.42 | |
HbA2 | 59.70 | 49.33 | 30.45 | 26.96 | |
β039/β039 | HbF | 48.41 | 31.74 | 67.77 | 40.44 |
α-peak | 25.91 | 8.26 | 14.82 | 5.91 | |
HbA | 1.05 | 44.71 | 1.84 | 41.47 | |
HbA2 | 23.99 | 14.93 | 15.39 | 11.79 |
Data represent the percent of the indicated hemoglobins (HbF, HbA, and HbA2). The α peak has been identified as a HPLC peak containing α-globin. T9W was used at MOI generating an average of one integration/genome. MTH was used at 50 nM