. Author manuscript; available in PMC: 2013 Aug 1.

Published in final edited form as: Exp Gerontol. 2012 May 14;47(8):601–607. doi: 10.1016/j.exger.2012.05.007

Table 3.

Myosin isoforms, muscle atrophy and function in vervet, human, and rat

	Species
	Vervet	Human	Rat
Myosin	Homologous to human myosin-1, -2, -4 & -7	MHC-1, -2, -4 & -7 in the skeletal muscle of adult (Andersen and Schiaffino 1997)	Homologous to human perinatal/myosin-8 (Feghali and Leinwand 1989)
BW	−24%	−13~26% per decade over 65 years old (Dziura and others 2004; Flynn and others 1989; Kenny and Prestwood 2000; Williamson 1993)	No significant decrease (Altun and others 2007)
CSA	↓ Type II > Type I	↓ Type II > Type I	No significant decrease (Schuenke and others 2011)
Physical performance	Slow walking speed (Shively and others 2011)	Slow gait speed (Cesari and others 2005)	Difficult to estimate due to different posture

BW: body weight; CSA: cross-sectional area