Figure 6.

Kaplan–Meir analysis of outcome in ER negative and triple-negative primary breast carcinomas according to methylation status of NT5E CpG island. Methylation in the NT5E CpG island was analysed by methylation-specific PCR and statistical analysis done as described in Materials and Methods. The top two panels show DFS (A) and OS (B) in ER-negative primary cancers either methylated (M) or unmethylated (U) in the NT5E CpG island. The lower two panels show DFS (C) and OS (D) in triple-negative breast carcinomas either M or U in the NT5E CpG island.