Table I.
Placebo group | Pivmecillinam 200mg×3×7d1 | Pivmecillinam 200mg×2×7d1 | Pivmecillinam 400mg×2×3d1 | Controls | |
Number of patients | 288 | 281 | 289 | 285 | 425 |
Age mean value (years) | 42 (±17) | 44 (±18) | 43 (±18) | 44 (±18) | 47 (±19) |
Age median and range (years) | 41 (18–82) | 44 (18–85) | 42 (18–88) | 40 (18–83) | 46 (18–89) |
Age distribution (%) ≤24 years | 23 | 22 | 20 | 21 | 17 |
25–54 years | 52 | 47 | 51 | 50 | 48 |
≥ 55 years | 25 | 31 | 29 | 29 | 35 |
Symptom duration (days) | |||||
Mean value (SD) | 9 (±16) | 11 (±22) | 9 (±21.0) | 10 (±18) | 7 (±12) |
Median | 4 | 4 | 4 | 5 | 3 |
Mean value of symptom scores (SD) | 5.3 (±2.0) | 5.5 (±2.0) | 5.2 (±2.0) | 5.3 (±2.0) | 5.5 (±.2.1) |
Mean bladder incubation time (hours) | 4 (±2) | 4 (±3) | 4 (±2) | 4 (±3) | 4 (±3) |
Significant bacteriuria (%) | |||||
E. coli | 59 | 67 | 61 | 62 | 62 |
Other species | 20 | 11 | 15 | 15 | 15 |
Negative culture | 22 | 23 | 24 | 23 | 23 |
1Days of treatment.