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. 2012 Mar;5(1):1–8. doi: 10.2478/v10102-012-0001-x

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Copyright© 2012 SETOX & IEPT, SASc

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Photomicrographs of brain histopathology of control, DDVP exposed and treated rats, H&E 40×. A: Control rat brain showing normal neuroglial cells arranged in several layers. B: DDVP exposed rat brain showing chromatolysis of nuclear material, gliosis and pyknotic neurons in cortex. C: Rat brain with DDVP + 2-PAMCl and atropine showing mild lesions of neuronal damage with moderate gliosis. D: 2-PAMCl + atropine + curcumin (200 mg/kg) treatment after DDVP exposure showing mild gliosis and chromatolysis along with minimal lesions of neuronal degeneration.