Table 3.
Joint effects between genotypes and smoking status.
| Genotype | Smoking | Cases n (%) | Control n (%) | Strata specific OR (95% CI) | Strata specific p value | Interaction OR (95% CI) | p-interaction |
|---|---|---|---|---|---|---|---|
| Rs4646421 | |||||||
| GG | No | 35 (22.3) | 48 (36.4) | Reference | |||
| GA+AA | No | 68 (43.3) | 61 (46.2) | 1.53 (0.84–2.77) | 0.134 | ||
| GG | Yes | 20 (12.7) | 11 (8.3) | Reference | |||
| GA+AA | Yes | 34 (27.7) | 12 (9.1) | 1.56 (0.52–4.69) | 0.377 | 1.54 (0.92–2.57) | 0.107 |
|
| |||||||
| rs1048943 | |||||||
| AA | No | 80 (51.0) | 84 (63.6) | Reference | |||
| AG+GG | No | 23 (14.6) | 25 (18.9) | 0.97 (0.48–1.93) | 0.916 | ||
| AA | Yes | 40 (25.5) | 17 (12.9) | Reference | |||
| AG+GG | Yes | 14 (8.9) | 6 (4.5) | 0.99 (0.29–3.70) | 0.988 | 0.97 (0.54–1.76) | 0.965 |
Abbreviations: CI, confidence interval; OR, odds ratio.