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. Author manuscript; available in PMC: 2012 Jul 5.
Published in final edited form as: J Am Chem Soc. 2011 Sep 28;133(41):16398–16401. doi: 10.1021/ja2033298

Figure 1.

Figure 1

Oxidative coupling reactions involving aniline groups on proteins. (a) The previously reported coupling between anilines and phenylene diamines occurs within 30–60 min. (b) The coupling between anilines and aminophenols occurs much faster, reaching high levels of conversion in under 2 min. (c) Reverse phase HPLC of 6a before and after purification indicated that the isolated compound was the major product in the reaction. (d) Product 6a was characterized using X-ray diffraction analysis.