Fig. 2.

Open-field and elevated plus-maze behaviors in control and DIO mice. DIO mice did not differ from controls in terms of (a) distance traveled during the open field test or (b) in terms of thigmotaxis. (c) DIO mice spent significantly less time within the open arms of the elevated plus maze than did controls [t(11) = 2.455, p < 0.05]. Asterisks indicate significant group differences between DIO mice compared to the chow-fed control group, as determined by unpaired t-tests. Error bars indicate s.e.m.