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CD28KO and B7KO mice have low numbers of IFN-γ-SCs in their peritoneal cavity. PerC cells (1.5×105) were stimulated with anti-CD3±anti-CD28. CI values represent the ratio of the CD28 costimulated response to the control response. *P<0.05. The data shown are representative of three separate trials that yielded similar data. IFN-γ-SC, interferon-γ-secreting cell; PerC, peritoneal cavity.
