Table IV.

Preoperative positive ratio (%) of urinary DiAcSpm, serum CEA and CA19-9 in patients with colorectal cancer.

TNM stage	No. of cases	Urinary DiAcSpm (%)	Serum CEA (%)	Serum CA19-9 (%)
0+I	19	66.7a	27.8	22.2
II	32	71.9b	46.9	15.7
III	39	48.7a	38.5	20.5
IV	23	100.0a	78.3	56.5
Total	113	69.0b	44.2	26.5

The positive rates of urinary DiAcSpm were significantly higher than those of serum CEA or CA19-9 in patients with all stages of CRC.

^ap<0.05,

^bp< 0.001.

DiAcSpm, N¹,N¹²-diacetylspermine; CEA, carcinoembryonic antigen; CA19-9, cancer antigen 19-9; TNM, Tumor-Node-Metastasis.