Table II.
Cytokine concentrations in AML patients and controls.
| Cytokine | Median (range) (pg/ml) | P-value | ||||
|---|---|---|---|---|---|---|
|
|
|
|||||
| AML ND | AML CR | Controls | ND vs. CR | ND vs. controls | CR vs. controls | |
| IL-35 | 107.40 (74.95–468.22) | 68.80 (48.07–252.47) | 63.23 (24.46–489.45) | 0.001a | 0.000a | 0.114 |
| IL-10 | 14.41 (6.39–59.20) | 8.47 (5.78–17.82) | 5.87 (4.29–7.78) | 0.000a | 0.000a | 0.000a |
| TGF-β | 377.31 (83.68–7220.11) | 285.39 (42.54–2172.26) | 1008.86 (250.28–33793.68) | 0.216 | 0.001a | 0.000a |
The Mann-Whitney test was used to compare the difference of cytokine concentrations between the two groups.
a
P<0.05 was considered statistically significant.
AML, acute myeloid leukemia; ND, newly diagnosed; CR, complete remission.