Table 1.

Effects of GSK2181236A or BAY 60-4552 on P-VASP formation in rat aortic smooth muscle cells.

	EC50 (nM)		Emax (% DMSO)
	Control	ODQ (10 μM)	Control	ODQ (10 μM)
GSK2181236A	12.7 ± 4.7	2.7 ± 0.6**	379 ± 26	502 ± 26*
BAY 60-4552	353 ± 89	3,264 ± 737***	388 ± 39	362 ± 24

All values are expressed as mean ± SEM (n = 4 independent experiments performed in at least duplicate). E_max values are expressed as relative fluorescence units normalized to DMSO vehicle. Statistical comparisons of vehicle- and ODQ-treated cells were performed using two-tailed t-tests where *P < 0.05, **P < 0.01, and ***P < 0.001 vs. vehicle control.