Expression of MIC-1 (lower panel) and GAPDH (upper panel) mRNA in different prostate lobes from prostate-specific antigen transgenic mice of different age groups. Lanes 3–5, young age; lanes 6–11, middle age; lanes 12–14, elderly. Lanes 3, 6, 9 and 12, dorsolateral prostate; lanes 4, 7, 10 and 13, ventral prostate; and lanes 5, 8, 11 and 14, anterior prostate. Lanes 1 and 2 are H2O and positive (RM11 mouse prostate tumor cells) controls, respectively.