Table III.
Correlation between the expression of nuclear Aurora B and cytoplasmic Survivin and pathological factors.
N+C+ | N+C− | N−C+ | N−C− | P-value | |
---|---|---|---|---|---|
Number of cases | 17 | 23 | 13 | 18 | |
Pathological features | |||||
Gender | |||||
Male | 8 | 11 | 5 | 8 | |
Female | 9 | 12 | 8 | 10 | |
Histological differentiation | |||||
Well/moderate | 12 | 20 | 12 | 17 | n.s |
Poor/mucinous | 5 | 3 | 1 | 1 | |
Lymph node metastasis | |||||
Negative | 4 | 19 | 12 | 17 | (N+C− vs. N+C−) (N+C− vs. N−C+) (N+C− vs. N−C−) (p<0.01) |
Positive | 13 | 4 | 2 | 1 | |
Lymphatic invasion | |||||
Negative | 0 | 2 | 1 | 1 | n.s |
Positive | 17 | 21 | 12 | 17 | |
Venous invasion | |||||
Negative | 1 | 0 | 1 | 1 | n.s |
Positive | 16 | 23 | 12 | 17 |
N+C+, positive nuclear Aurora B and positive cytoplasmic Survivin expression; N+C−, positive nuclear Aurora B and negative cytoplasmic Survivin expression; N−C+, negative nuclear Aurora B and positive cytoplasmic Survivin expression; N−C−, negative nuclear Aurora B and negative cytoplasmic Survivin expression; n.s., not significant.