Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Alternative polyadenylation leads to TIN between opposing genes. The Mest and Copg2 genes are positioned in a convergent orientation relative to each other on the mouse DNA. Transcription of the Mest gene is terminated “normally,” without overlapping with the Copg2 gene in embryonic liver cells (A), whereas Mest transcription is continued within the Copg2 gene in neurons, thereby reducing the expression of this gene (B).
