Table 1.
Genes up-regulated in BMSCs | Fold- Increase | Genes down-regulated in BMSCs | Fold- Decrease | ||
---|---|---|---|---|---|
TGFBI | transforming growth factor, beta-induced | 346 | LAPTM5 | lysosomal multispanning membrane protein 5 | 74.3 |
COL3A1 | collagen, type III, alpha 1 | 153 | HLA-DRA | histocompatibility antigen HLA-DR | 54.1 |
ADAM12 | ADAM metallopeptidase domain 12 | 90.7 | GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 43.5 |
ACTA2 | actin, alpha 2, smooth muscle, aorta | 87.8 | MPO | myeloperoxidase | 35.3 |
ANXA2 | annexin A2 | 65.5 | GMFG | glia maturation factor, gamma | 35.3 |
CTGF | connective tissue growth factor | 64.2 | CCND2 | cyclin D2 | 34.3 |
PENK | proenkephalin | 62.4 | PRSSL1 | protease, serine-like 1 | 33.2 |
MXRA8 | matrix-remodelling associated 8 | 62.1 | ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | 31.96 |
COL3A1 | collagen, type III, alpha 1 | 58.5 | ACSS1 | acyl-CoA synthetase short-chain family member 1 | 31.89 |
MYOF | myoferlin | 57.8 | SYK | spleen tyrosine kinase, transcript variant 2 | 29.47 |
FEZ1 | fasciculation and elongation protein zeta 1 | 57.7 | HLA-DPB1 | MHC, class II, DP beta 1 | 26.36 |
NCKAP1 | NCK-associated protein 1 | 53.5 | GBP4 | guanylate binding protein 4 | 25.55 |
NQO1 | NAD(P)H dehydrogenase, quinone 1 | 52.4 | IGHG1 | Immunoglobulin lambda heavy chain | 25.46 |
FN1 | fibronectin 1 ( | 51.4 | ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | 25.36 |
PCOLCE | procollagen C-endopeptidase enhancer | 47.5 | H1FX | H1 histone family, member X | 22.86 |
AFAP1 | actin filament associated protein 1 | 46.7 | ICAM3 | intercellular adhesion molecule 3 | 22.06 |
THBS1 | thrombospondin 1 | 43.4 | HLA-DRB3 | MHC, class II, DR beta 3 | 21.79 |
AMOTL2 | angiomotin like 2 | 42.9 | HLA-DRA | MHC, class II, DR alpha | 21.71 |
CTSL1 | cathepsin L1 | 42.3 | HLA-DRB4 | MHC, class II, DR beta 4 | 21.40 |
LARP6 | La ribonucleoprotein domain family, member 6 | 37.9 | SELL | selectin L | 20.90 |
MT2A | metallothionein 2A | 37.7 | HLA-DMA | MHC, class II, DM alpha | 20.84 |
SLC17A8 | solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8 | 37.4 | LOC100131564 | (xs92) mRNA, 445bp | 19.45 |
ACTN1 | actinin, alpha 1 | 37.4 | STAG3L2 | PREDICTED: Homo sapiens hypothetical protein LOC100132740 | 18.48 |
ITGB5 | integrin, beta 5 | 36.8 | CYTL1 | cytokine-like 1 | 18.05 |
FN1 | fibronectin 1, transcript variant 5 | 36.1 | CHST13 | carbohydrate (chondroitin 4) sulfotransferase 13 | 17.88 |
p < 1 × 10−3 for all genes