Table 3.
Genes differentially expressed between BMSCs and fibroblasts.
| Genes up-regulated most in BMSCs | Fold Increase | Genes down-regulated most in BMSCs Name | Fold Decrease | ||
|---|---|---|---|---|---|
| HAPLN1 | hyaluronan and proteoglycan link protein 1 | 21.9 | MMP3 | matrix metallopeptidase 3 (stromelysin 1, progelatinase) | 51.0 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | 7.72 | CPZ | carboxypeptidase Z | 39.2 |
| HAS2 | hyaluronan synthase 2 | 7.46 | MASP1 | mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) | 18.1 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 6.76 | PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) | 15.1 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 6.71 | MME | membrane metallo-endopeptidase | 13.6 |
| GALNT1 | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N- acetylgalactosaminyltransferase 1 (GalNAc-T1) | 6.65 | SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 | 13.1 |
| ALDH1B1 | aldehyde dehydrogenase 1 family | 6.63 | TWIST2 | twist homolog 2 (Drosophila) | 12.7 |
| SIAE | sialic acid acetylesterase | 6.46 | SFRP1 | secreted frizzled-related protein 1 | 12.7 |
| SORCS2 | sortilin-related VPS10 domain containing receptor 2 | 6.18 | OSR2 | odd-skipped related 2 (Drosophila) | 12.3 |
| HOXB7 | homeobox B7 | 5.84 | CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 10.4 |
| SMAD7 | SMAD family member 7 | 5.61 | CTSC | cathepsin C | 10.1 |
| LCTL | lactase-like | 5.59 | EMILIN2 | elastin microfibril interfacer 2 | 9.25 |
| ETV7 | ets variant 7 | 5.52 | HSPB3 | heat shock 27kDa protein 3 | 9.18 |
| ANKH | ankylosis | 5.49 | ADM | adrenomedullin | 8.79 |
| PASD1 | PAS domain containing 1 | 5.36 | FAM129A | family with sequence similarity 129, member A | 8.45 |
| P2RY6 | pyrimidinergic receptor P2Y | 5.26 | CXCR7 | Chemokine (C-X-C motif) receptor 7 | 8.41 |
| FN1 | fibronectin 1 | 5.07 | TSEN54 | tRNA splicing endonuclease 54 homolog (S. cerevisiae) | 8.16 |
| VCAN | versican | 4.95 | COL15A1 | Collagen, type XV, alpha 1 | 8.09 |
| KCNH2 | potassium voltage-gated channel | 4.90 | PTGFR | prostaglandin F receptor | 8.03 |
| VCAM1 | vascular cell adhesion molecule 1 | 4.88 | CD69 | CD69 molecule | 7.65 |
| ABI3BP | ABI family | 4.83 | WWOX | WW domain containing oxidoreductase | 7.47 |
| TTC3 | tetratricopeptide repeat domain 3 | 4.65 | IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 7.08 |
| PDLIM5 | PDZ and LIM domain 5 | 4.63 | PDPN | podoplanin | 7.01 |
| SLC22A6 | solute carrier family 22 (organic anion transporter) | 4.56 | CTSC | cathepsin C | 6.61 |
| DACT1 | dapper | 4.52 | DPP4 | dipeptidyl-peptidase 4 | 6.58 |
P < 1 × 10−2 for all genes