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. Author manuscript; available in PMC: 2013 Jun 28.
Published in final edited form as: J Control Release. 2012 Apr 10;160(3):561–569. doi: 10.1016/j.jconrel.2012.04.005

Figure 7. Positive gene expression from microneedle-coated pDNA delivered to viable human skin.

Figure 7

(A) En face image of a single point of gene expression from a plasmid encoding β-galactosidase with the microneedle device as a scale reference. (B) A H&E stained 10 μm histological section of human skin showing the point of microneedle penetration and the positive gene expression from the delivered dry coated plasmid encoding β-galactosidase (bar = 100μm). (C) Human epidermal sheet treated with a microneedle device dry-coated with a plasmid encoding EGFP (bar = 100μm).

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