Figure 3. Reduced number of GABAergic interneurons in Cntnap2−/− mice.
(A) Network plot showing the top 300 connections within the Cntnap2 module (B) Expression of Gad1 at P14 shows a reduced number of GABAergic interneurons in somatosensory cortex of KO mice. Scale bar: 50µm (C) Expression of the interneuron markers PAVLB, CALB2, and NPY at P14. Scale bar: 50µm (D) Expression of the GABAergic interneurons PAVLB and NPY in striatum. Scale bar: 100µm. Interneuron quantification is shown as % of WT. *p<0.05, **p<0.01, ***p<0.001. For (B), (C), (D) and (E) n=4 mice/genotype. Data are presented as mean ± S.E.M. See also Table S2 and Figure S3.