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Decreased mitochondrial depolarization after hemorrhage and resuscitation of JNK2-deficient mice. Multiphoton imaging of hepatic Rh123 fluorescence was performed at 4 h after sham operation to wildtype mice (a) and H/R of wildtype- (b) and JNK2-deficient (c) mice, as described in Section 2. The percentage of hepatocytes per HPF with depolarized mitochondria is plotted in (d). Bar is 10 μm. P < 0.05 versus other groups; n = 3 per group.
