Table 2. Clinically important cytochrome P450 (CYP) isozymes and substrates.
CYP1A2 | CYP2C9 | CYP2C19 | CYP2D6 | CYP3A4 |
Mexiletine | Phenytoin | Phenytoin | Flecainide | Quinidine |
Caffeine | Warfarin | Diazepam | Encainide | Disopyramide |
Theophylline | Propafenone | Lidocaine | ||
Mexiletine | Amiodarone | |||
Metoprolol | Verapamil |