Figure 2. Gene and protein expression levels of RAMP1 (A, E), RAMP2 (B, F), RAMP3 (C, G) and CRLR (D, H) in the aorta of WKYs, SHRs, adrenomedullin-treated SHRs (SHR+ADM) and intermedin 1-47-treated SHRs (SHR+IMD 1-47). Data are expressed as means ± SE, ^*P < 0.05 and ^#P < 0.01, vs. SHR, ^†P < 0.05 vs. SHR + IMD. RAMPs: receptor activity-modifying proteins; CRLR: calcitonin receptor-like receptor; WKYs: Wistar Kyoto (WKY) rats group; SHRs: spontaneously hypertensive rats group. n = 11 in each group.